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From raw audio to structure: an agent-based pipeline that boosts medical LLM performance
Hao Qin1, Wenjun Tang2, Zigeng Huang2
1Department of Medical Bioinformatics, School of Basic Medical Sciences, Peking University, Beijing, China.
This study introduces an agent-based framework to automatically structure noisy clinical conversations for training large language models (LLMs). The structured data significantly improves LLM performance in medical dialogue tasks.
Area of Science:
- Artificial Intelligence
- Computational Linguistics
- Medical Informatics
Background:
- Large language models (LLMs) require high-quality conversational data for clinical communication applications.
- Real-world clinical recordings are often degraded by noise, transcription errors, and fragmented dialogue, limiting their utility for training LLMs.
Purpose of the Study:
- To develop an agent-based transcription framework to convert raw unstructured clinical conversation transcriptions (RUCT) into structured conversation transcriptions (SCT).
- To evaluate the framework's accuracy, speed, and impact on downstream LLM fine-tuning for medical dialogue.
Main Methods:
- An agent-based system with Planner, Memory, and Executor modules was designed for noise removal, content correction, speaker identification, and dialogue segmentation.
- The framework was applied to Chinese and English clinical recordings, and its performance was compared against other methods.
- An independent LLM (Qwen3-32B) was fine-tuned using agent-generated SCT and RUCT for comparative analysis.
Main Results:
- The agent achieved high reconstruction accuracy: 94.7% denoising, 96.9% content correction, 88.6% speaker identification, and 92.7% segmentation.
- The framework operated 3.6x faster than manual processing and outperformed cascaded deep-learning and end-to-end models.
- Fine-tuning LLMs on agent-generated SCT significantly improved quality scores (3.1 to 3.7) and benchmark performance compared to RUCT fine-tuning.
Conclusions:
- Agent-structured clinical corpora enhance LLM fine-tuning performance for medical dialogue applications.
- The developed framework offers a scalable solution for creating reliable medical conversational AI by improving data quality.
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