Related Experiment Video

Updated: Jun 10, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

CXCR4 Facilitates Osteosarcoma Progression through MMP9-Mediated Cell Migration and Matrix Degradation

Hanyong Zhang1, Mengchang Xu1, Yan Jiang2

  • 1Changsha Medical University Hunan Key Laboratory Of The Research And Development Of Novel Pharmaceutical PreparationsProvincial first-class applied discipline (pharmacy) Changsha China.

Current Cancer Drug Targets
|June 9, 2026
PubMed
Summary

CXCR4 promotes osteosarcoma cell invasion by increasing MMP9. Targeting the CXCR4-MMP9 pathway could be a new strategy against bone cancer metastasis.

Keywords:
CXCR4Cell invasionMMP9Matrix degradationOsteosarcoma

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