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Related Experiment Videos

Examining BRITEpath, a Digital Intervention for Reducing Adolescent Suicide Risk in Primary Care: A

Nermin Toukhy1, Candice Biernesser1, Jamie Zelazny1

  • 1Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Suicide & Life-Threatening Behavior
|June 9, 2026
PubMed
Summary

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Community Based Intervention01:30

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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The BRITEpath app showed promising results in reducing suicidal thoughts among adolescents in primary care. While not improving all outcomes, it demonstrated potential for managing youth suicide risk, especially for those with prior psychiatric care.

Area of Science:

  • Adolescent mental health
  • Digital health interventions
  • Suicide prevention

Background:

  • Primary care settings have a high need for adolescent suicide risk management.
  • Smartphone-based applications offer a novel approach to address this need.
  • The BRITEpath intervention was developed to aid youth in reducing suicide risk.

Purpose of the Study:

  • To examine the efficacy and feasibility of the BRITEpath smartphone application and clinician portal.
  • To assess BRITEpath's impact on suicidal thoughts and behaviors, depression, mental health service use, and quality of life in adolescents.
  • To evaluate user satisfaction and perceived usefulness of the BRITEpath intervention.

Main Methods:

  • A randomized controlled trial with 101 participants (ages 12-26) was conducted.
Keywords:
adolescentsdigital health interventionprimary caresmartphone appsuicide risk

Related Experiment Videos

  • Participants were assigned to either BRITEpath plus treatment as usual (TAU) or TAU alone.
  • Outcomes were assessed by blinded evaluators at baseline, week 4, and week 12.
  • Main Results:

    • No significant differences were observed for primary outcomes between the BRITEpath + TAU and TAU groups overall.
    • BRITEpath participants reported a significant reduction in suicidal thoughts over the study period.
    • High user satisfaction and perceived usefulness of the BRITEpath app were reported, with effects on depression moderated by prior psychiatric care history.

    Conclusions:

    • The BRITEpath intervention shows promise for reducing suicidal thoughts and improving depression symptoms in adolescents, particularly those with a history of psychiatric care.
    • Further research is needed to optimize engagement strategies, such as integrating BRITEpath with ongoing clinical care, to enhance its impact.
    • Smartphone-based tools like BRITEpath represent a feasible and potentially effective component of adolescent suicide risk management in primary care settings.