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Related Experiment Video

Updated: Jun 10, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

Swept-Source OCT Biometry-Derived Corneal Optical Quality: Repeatability Limits for IOL Design Selection in

Stefan Georgiev1, Manuel Ruiss1, Rainer A Leitgeb2

  • 1Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria and.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|June 9, 2026
PubMed
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Swept-source optical coherence tomography (SS-OCT) biometry reliably measures corneal optical quality for cataract surgery. These metrics aid intraocular lens selection, but repeatability limits must be considered for accurate clinical decisions.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optical Metrology

Background:

  • Accurate corneal optical quality assessment is crucial for refractive cataract surgery.
  • Intraocular lens (IOL) selection and surgical outcomes depend on precise biometric data.
  • Swept-source optical coherence tomography (SS-OCT) offers advanced biometry capabilities.

Purpose of the Study:

  • To evaluate the reliability of corneal optical quality metrics derived from SS-OCT biometry.
  • To assess the impact of these metrics on intraocular lens design selection in refractive cataract surgery.
  • To provide the first reliability analysis of SS-OCT biometry for corneal optical quality.

Main Methods:

  • Retrospective instrument evaluation of SS-OCT biometer (ANTERION) scans.

Related Experiment Videos

Last Updated: Jun 10, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
05:14

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter

Published on: September 16, 2025

  • Analysis of corneal higher order aberrations (HOAs) using Zernike polynomial decomposition.
  • Calculation of repeatability metrics including pooled within-subject standard deviation (Sw), coefficient of variation, and intraclass correlation coefficient (ICC).

    • Main Results:

    • High repeatability for anterior, posterior, and total HOAs with repeatability limits below 0.10 µm at a 4-mm optical zone.
    • Excellent intraclass correlation coefficients (ICCs) ranging from 0.76 to 0.97.
    • Root mean square HOA and spherical aberration showed strong repeatability (ICC: 0.89 and 0.84, respectively).

    Conclusions:

    • SS-OCT biometry reliably characterizes corneal optical quality at clinically relevant zones.
    • Repeatability limits are essential for informed IOL design selection and outcome-based research.
    • Measurement uncertainty necessitates consideration of repeatability data in clinical decision-making.