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Related Concept Videos

Chirality in Nature02:30

Chirality in Nature

Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid. The...
Chirality02:25

Chirality

Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Prochirality02:05

Prochirality

The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
SN1 Reaction: Stereochemistry02:15

SN1 Reaction: Stereochemistry

This lesson provides an in-depth discussion of the stereochemical outcomes in an SN1 reaction.
In the first step of an SN1 reaction, the bond between the electrophilic carbon and the leaving group ionizes to generate the carbocation intermediate. The second step of the mechanism is the nucleophilic attack.
In the formed carbocation, the positively charged carbon is sp2 hybridized with a trigonal planar geometry. As all the three substituents lie on the same plane, a plane of symmetry for the...

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Updated: Jun 10, 2026

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
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Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

An argument why the spinterface model cannot explain the chirality induced spin selectivity effect.

J Fransson1

  • 1Department of Physics and Astronomy, Uppsala University, P.O. Box 516, 75 237 Uppsala, Sweden.

The Journal of Chemical Physics
|June 9, 2026
PubMed
Summary
This summary is machine-generated.

Chiral molecules on metals do not form local spin moments, even with strong spin-orbit coupling. Electron flux, spin-polarized or not, also fails to induce spin moment formation at the interface.

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Area of Science:

  • Surface Science
  • Condensed Matter Physics
  • Quantum Chemistry

Background:

  • Chirality-induced spin selectivity (CISS) is a phenomenon where chiral molecules influence electron spin.
  • Previous theories suggested chiral molecules on metals could form local spin moments due to strong spin-orbit coupling (SOC).

Purpose of the Study:

  • To analyze the conditions for local spin moment formation at chiral molecule-metal interfaces.
  • To investigate the role of strong spin-orbit coupling in sustaining spin moments.
  • To determine if electron flux influences spin moment formation.

Main Methods:

  • General theoretical arguments.
  • Effective modeling of a chiral molecule-metal interface setup.

Main Results:

  • Strong spin-orbit coupling in metals is insufficient to stabilize a local spin moment at the interface.
  • Electron flux into or out of the molecule does not lead to spin moment formation.
  • This holds true irrespective of the spin polarization of the electron flux.

Conclusions:

  • The proposed mechanism for spin moment formation via strong SOC is not viable.
  • Electron flux is not a viable pathway for inducing spin moments in this system.
  • Revisiting the fundamental mechanisms of spin selectivity in chiral systems is warranted.