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Intra-cranial Calcification on Cross-sectional Imaging - A Pictorial Review.

Lokesh Rana¹, Dileep Chowdary¹, Vinay Sharma¹

¹Department of Radiology, AIIMS, Bilaspur, Himachal Pradesh, India.

Annals of African Medicine

|June 9, 2026

Summary

Intra-cranial calcifications are common brain findings with diverse causes. This review details physiological, pathological, and age-related calcifications, aiding diagnosis through characteristic patterns and clinical scenarios.

Keywords:

Intracranial calcification calcifications intracrâniennes pathological pathologiques physiological physiologiques

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Area of Science:

Radiology
Neurology
Pathology

Background:

Intra-cranial calcification is a frequent observation in neuroimaging.
Causes range from physiological and age-related to congenital infections, genetic, metabolic, endocrine, neoplastic, and inflammatory disorders.

Purpose of the Study:

To review physiological, pathological, and age-related intra-cranial calcifications.
To correlate calcification patterns with specific clinical scenarios for diagnostic purposes.

Main Methods:

Review of existing literature on intra-cranial calcifications.
Analysis of imaging findings (CT and MRI) and associated clinical data.

Main Results:

Detailed description of various types of intra-cranial calcifications.
Identification of characteristic calcification patterns linked to underlying etiologies.

Conclusions:

Understanding the diverse causes and patterns of intra-cranial calcification is crucial for accurate diagnosis.
This review provides a framework for interpreting brain calcifications in both pediatric and adult populations.