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Related Experiment Video

Updated: Jun 11, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
12:10

Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

Enhancing Continence Recovery After Robot-Assisted Radical Prostatectomy: A Novel Combined Approach Using

Yasunari Tanaka1, Fumitaka Shimizu1, Abulaiti Abudurezake2

  • 1Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

The Prostate
|June 9, 2026
PubMed
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This summary is machine-generated.

Testosterone replacement therapy (TRT) reduced urinary incontinence (UI) after prostatectomy. Combining TRT with magnetic stimulation (MS) may improve pelvic floor muscle (PFM) volume and urinary symptoms, but more research is needed.

Area of Science:

  • Urology
  • Andrology
  • Reconstructive Surgery

Background:

  • Persistent urinary incontinence (UI) is a common issue post-robot-assisted radical prostatectomy (RARP), impacting patient quality of life.
  • Late-onset hypogonadism (LOH) may be a contributing factor in some patients with post-RARP UI.

Purpose of the Study:

  • To investigate the effects of testosterone replacement therapy (TRT) on UI and pelvic floor muscle (PFM) volume in patients with persistent UI after RARP.
  • To evaluate the additional benefit of magnetic stimulation (MS) when combined with TRT.

Main Methods:

  • A 6-month TRT protocol was administered to patients with persistent UI post-RARP and LOH, excluding those with cancer recurrence.
  • Pelvic floor muscle (PFM) volume was assessed using thin-slice computed tomography.
Keywords:
late‐onset hypogonadismmagnetic stimulationpelvic floor musclerobot‐assisted radical prostatectomytestosterone replacement therapyurinary incontinence

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  • Urinary symptoms, pad tests, and blood markers were evaluated pre- and post-treatment. Some patients received additional magnetic stimulation (MS).

    • Main Results:

    • TRT significantly reduced urinary incontinence (pad weight decreased by 44.1g).
    • The combination of TRT and MS led to significant improvements in urinary symptom questionnaire scores (OABSS, IPSS, IPSS-QOL).
    • TRT with MS significantly increased PFM volume (6.3mL), with greater gains compared to other muscle parameters. No biochemical recurrence was observed.

    Conclusions:

    • Testosterone replacement therapy (TRT) shows promise in reducing urinary incontinence (UI) after RARP.
    • The combination of TRT and magnetic stimulation (MS) may enhance PFM volume and improve urinary symptom scores.
    • Further studies are required to confirm the synergistic effects of TRT and MS on post-prostatectomy UI.