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Updated: Jun 11, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Deep learning of SHERLOC Raman spectra for facilitating Mars Astromaterial identification.
Likun Wang1, Jing Tian1, Mengna Cai2
1Qian Xuesen Collaborative Research Center of Astrochemistry and Space Life Sciences, Institute of Drug Discovery Technology, Ningbo University, Ningbo 315211, China.
Deep learning models accurately identify minerals from Mars Raman spectra, aiding automated astromaterial discovery. This research benchmarks machine learning for planetary exploration, enhancing spectral interpretation capabilities.
Area of Science:
- Planetary Science
- Astrobiology
- Spectroscopy
Background:
- Raman spectroscopy is crucial for planetary exploration, particularly for identifying potential biosignatures and materials on Mars using instruments like SHERLOC.
- Current astromaterial identification relies heavily on expert analysis of comparative Raman spectra, which can be time-consuming and subjective.
Purpose of the Study:
- To benchmark machine learning (ML) and deep learning (DL) models for automated identification of mineral classes from SHERLOC Raman spectra.
- To evaluate the performance of DL models in identifying astromaterials under class-imbalanced conditions.
Main Methods:
- Benchmarking three ML and two DL models using expert-labeled SHERLOC Raman spectra from Mars missions (Crater Floor and Upper Fan campaigns).
- Applying the best-performing DL model to unlabeled and non-diagnostic spectra to assess its predictive consistency.
Main Results:
- The top-performing DL model achieved 89.3% accuracy in identifying six mineral classes.
- The DL model demonstrated competitive class-wise performance even with imbalanced datasets.
- Predictions on unlabeled spectra aligned with known material characteristics from existing literature.
Conclusions:
- Deep learning models show significant potential for high-performance, automated astromaterial identification from Raman spectra.
- DL methods can enhance spectral interpretation and support future planetary exploration missions.
- This study provides a foundation for integrating AI-driven spectral analysis in the search for extraterrestrial materials.
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