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Related Experiment Video

Updated: Jun 11, 2026

Establishing a Competing Risk Regression Nomogram Model for Survival Data

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Published on: October 23, 2020

Spatial Disparities in Stage-Specific Breast Cancer Incidence and Area-Level Risk Factors in Korea, 2005-2018.

Eun Hye Park^1,2, Kyu-Won Jung^3,4, Seung-Sik Hwang⁵

¹Korea Central Cancer Registry, National Cancer Center, Goyang, Korea.

Cancer Research and Treatment

|June 9, 2026

Summary

Spatial disparities in breast cancer stage at diagnosis in Korea are linked to area-level factors like deprivation and healthcare access. Addressing these disparities is crucial for improving early detection and patient outcomes.

Keywords:

Breast neoplasms Incidence Korea Neoplasm staging Spatial analysis

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Area of Science:

Oncology
Public Health
Spatial Epidemiology

Background:

Despite a national breast cancer screening program in Korea, significant spatial variations in diagnosis stage persist.
These disparities can lead to unequal treatment outcomes and reduced survival rates.

Purpose of the Study:

To investigate the spatial disparities in breast cancer incidence by stage at diagnosis across Korean municipalities.
To examine the association between these stage-specific incidence patterns and area-level risk factors.

Main Methods:

A population-based ecological study utilized data from the Korea National Cancer Incidence Database (2005-2018).
Stage-specific breast cancer incidence was estimated for 250 municipalities over three time periods.
Bayesian hierarchical models assessed associations with area deprivation index (ADI), obesity, alcohol consumption, screening rates, and mammography availability.

Main Results:

Localized-stage breast cancer incidence was higher in affluent areas, while distant-stage incidence was more prevalent in deprived areas.
Lower ADI, lower obesity rates, and higher mammography availability were linked to higher localized-stage incidence.
Higher ADI and increased alcohol consumption were significantly associated with higher distant-stage incidence.

Conclusions:

Spatial disparities in breast cancer stage at diagnosis in Korea are influenced by area-level socioeconomic status, healthcare resources, and lifestyle behaviors.
Integrating spatial analysis into cancer control strategies is essential for promoting equitable early detection and improving breast cancer outcomes.