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Updated: Jun 11, 2026

A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method
Published on: September 30, 2017
Effectiveness of diathermy in reducing subcutaneous adipose tissue affected by lipedema: a pilot study
Edurne Úbeda-D'Ocasar1, Mar Dodero-Paz2, Noemí Mayoral-Gonzalo1
1Physiotherapy and Health Research Group (FYSA), Faculty of Health Sciences - HM Hospitals, University Camilo José Cela, Urb. Villafranca del Castillo, 49. 28692. Villanueva de la Cañada, Madrid, Spain; Instituto de Investigación Sanitaria HM Hospitales, Madrid, 28015, Spain.
Background:
Lipedema is a painful subcutaneous adipose tissue (SAT) disorder that mainly affects women. Patients present fat accumulation in the limbs, especially in the legs.
Methods:
A pilot-controlled clinical trial was conducted on a sample of 18 patients with lipedema, equally divided into a control group (CG) and an experimental group (EG). Both groups were given 10 sessions of diathermy on the inner side of their knees, 10 min of treatment per knee. EG was given the diathermy dose at high-intensity heat, while CG was given sham treatment. Measurement instruments used were circumferential measurements, ultrasound measurements, algometry, VAS, and SF-12 questionnaire. Data were collected at baseline, at the end of the study and 5 weeks later.
Results:
significant reductions in left knee circumference were observed in the EG compared with the CG (p = 0.004 post-intervention and p = 0.017 at follow-up). No significant differences were found in ultrasound, algometry, or VAS measurements within or between groups.
Conclusions:
High-intensity heat diathermy resulted in a reduction in knee circumference, suggesting a potential effect on limb volume.

