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Synergistic Dual-Nano Delivery Systems for Enhanced Foliar Deposition and Disease Control
Xinglong Xu1, Jinghui Zhan1,2, Cailing Meng1
1Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China.
Journal of Agricultural and Food Chemistry
|June 10, 2026
Summary
Two novel leaf-adhesive nanopesticide systems enhance crop protection by combining difenoconazole and pyraclostrobin. These green formulations improve fungicide efficiency and reduce environmental impact for sustainable agriculture.
Area of Science:
- Agricultural Science
- Nanotechnology
- Environmental Science
Background:
- Pesticides are crucial for food security but suffer from low efficiency and environmental concerns.
- Developing sustainable agricultural practices requires innovative pesticide delivery systems.
Purpose of the Study:
- To create green, leaf-adhesive nanodelivery systems for enhanced pesticide efficacy.
- To evaluate the performance of nanoemulsion and nanosuspension formulations of difenoconazole and pyraclostrobin.
Main Methods:
- Developed a carrier-free nanoemulsion (DIF-PYR NE) and a biodegradable PLGA-based nanosuspension (DIF-PYR NS).
- Assessed plant interactions (wetting, foliar deposition) and antifungal activity against key plant pathogens.
- Investigated controlled-release profiles and antifungal mechanisms.
Main Results:
- Both nanoformulations showed uniform size, good dispersibility, and favorable environmental safety.
- DIF-PYR NE provided rapid, broad-spectrum control of fungal diseases.
- DIF-PYR NS offered sustained antifungal efficacy.
- Significantly enhanced control of *Botrytis cinerea*, *Fusarium oxysporum*, and *Fusarium graminearum* compared to conventional formulations.
Conclusions:
- Established a versatile, efficient, and ecobenign nanopesticide platform for sustainable crop protection.
- The developed nanodelivery systems offer a promising solution to improve pesticide utilization efficiency and reduce environmental impact.
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