Related Experiment Videos
Gastrointestinal Beriberi Secondary to Intermittent Hemodialysis With Rapid Improvement Following Thiamine
Benjamin Dale Day1, Jacelyn Emily Peabody Lever2, Kathryn Vickers1
1Department of Internal Medicine, Tinsley Harrison Internal Medicine Residency Program, University of Alabama at Birmingham, Birmingham, Alabama, USA, uab.edu.
Abstract:
Thiamine deficiency is classically linked to malnutrition and chronic alcohol use, but emerging evidence indicates that patients on intermittent hemodialysis (iHD) are also at significant risk. While cardiovascular and neurologic syndromes are well characterized, gastrointestinal (GI) beriberi remains an underrecognized presentation. We describe a 67-year-old man on iHD with chronic abdominal pain, nausea, vomiting, and anorexia refractory to conventional therapy. Workup revealed elevated lactate and a low plasma thiamine level prior to supplementation. Symptoms and elevated lactate resolved rapidly following intravenous thiamine. This case underscores GI beriberi as a treatable cause of chronic GI symptoms in dialysis patients.
Related Concept Videos
Hemodialysis III: Nursing Management
Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease III: Interprofessional Care
Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Chronic Kidney Disease IV: Nursing Management
Hemodialysis I: Introduction