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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Surface Modification of Titanium Using Nano-Hydroxyapatite: A Comparative Microhardness Study.

Shazia Kosar¹, Mohd Ali¹, Vidhi Sangra²

¹Department of Prosthodontics and Crown and Bridge, Government Dental College and Hospital, Srinagar, IND.

|June 10, 2026

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Nano-hydroxyapatite surface modification significantly enhanced the microhardness of titanium discs. This biomimetic material improves surface durability, suggesting better clinical performance and osseointegration for dental implants.

Area of Science:

Biomaterials Science
Surface Engineering
Dental Implantology

Background:

Surface modification of titanium implants is crucial for improving mechanical and biological properties.
Nano-hydroxyapatite (nHA) is a promising biomimetic material for enhancing implant surfaces.
Optimizing implant surface characteristics is key to successful osseointegration and longevity.

Purpose of the Study:

To evaluate the effect of nano-hydroxyapatite on the surface microhardness of titanium discs.
To determine if nHA treatment enhances the mechanical integrity of titanium surfaces.
To assess the potential of nHA for improving implant durability.

Main Methods:

An in vitro experimental study using 30 commercially pure titanium discs.

Keywords:

biomaterials dental implants nano-hydroxyapatite surface microhardness titanium

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Two groups: control (artificial saliva) and experimental (nano-hydroxyapatite treatment).

Vickers microhardness testing was performed before and after a 14-day treatment period.

Main Results:

Baseline microhardness was comparable between groups (approx. 224 VHN).
The nano-hydroxyapatite group showed a significant increase in microhardness (241.65 VHN).
The control group exhibited a slight decrease in microhardness (222.01 VHN), with a highly significant intergroup difference (p < 0.001).

Conclusions:

Nano-hydroxyapatite surface modification significantly improves titanium microhardness.
Enhanced microhardness suggests increased surface durability and resistance to wear.
These findings indicate potential for improved clinical performance and osseointegration of dental implants.