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Updated: Jun 11, 2026

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Sarcoidosis and Obstructive Sleep Apnoea: An Intriguing Relationship.

Ubaldo Ciccarelli¹, Paolo Ghelardini¹, Maria Chiara Pisciella¹

¹Facoltà di Medicina e Chirurgia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

The Open Respiratory Medicine Journal

|June 10, 2026

Summary

Patients with sarcoidosis often experience fatigue and excessive daytime sleepiness due to a higher prevalence of obstructive sleep apnoea (OSA). Screening for OSA and treatments like CPAP can improve quality of life.

Keywords:

CPAP therapy Excessive daytime sleepiness Fatigue Obstructive sleep apnoea Sarcoidosis Sleep disorders

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Area of Science:

Pulmonary Medicine
Sleep Medicine
Immunology

Background:

Sarcoidosis is a multisystem granulomatous disease with unknown cause, frequently impacting lungs.
Fatigue and excessive daytime sleepiness (EDS) are common, disabling symptoms in sarcoidosis patients, persisting even with stable disease.
Obstructive sleep apnoea (OSA) is increasingly recognized as prevalent in sarcoidosis, linked by inflammation, corticosteroid therapy, and airway involvement.

Purpose of the Study:

To explore the complex association between sarcoidosis and obstructive sleep apnoea (OSA).
To understand the contributing mechanisms linking sarcoidosis and OSA.
To highlight the importance of OSA screening and treatment in sarcoidosis patients with sleep-related symptoms.

Main Methods:

Review of existing clinical studies and evidence.
Analysis of shared inflammatory pathways and treatment side effects.
Assessment of upper airway involvement and pulmonary function in sarcoidosis patients.

Main Results:

Sarcoidosis patients exhibit a higher prevalence of OSA than the general population, including non-obese and treatment-naïve individuals.
Mechanisms include shared inflammation, corticosteroid-induced weight gain/myopathy, upper airway sarcoidosis (SURT), and restrictive lung disease.
Continuous Positive Airway Pressure (CPAP) therapy improves fatigue, EDS, and quality of life in these patients.

Conclusions:

OSA is a significant contributor to fatigue and EDS in sarcoidosis.
Systematic OSA screening is crucial for sarcoidosis patients with persistent sleep symptoms.
Further research is needed on OSA treatment impact and adjunctive therapies like solriamfetol and pitolisant.