Thoracoscopic Sympathectomy for Chronic Recurrent and Intractable Ventricular Tachycardia: A Case Series
Benjamin Grobman1, Geriam Ruiz-Barreto2,3, Anupama Singh3,4
1Harvard Medical School, Boston, Massachusetts.
Annals of Thoracic Surgery Short Reports
|June 10, 2026
Summary
Thoracoscopic sympathectomy offers relief for intractable ventricular tachycardia when ablation fails. This procedure is well-tolerated and can significantly reduce symptoms or achieve remission in select patients with refractory cardiac arrhythmias.
Area of Science:
- Cardiology
- Thoracic Surgery
- Autonomic Nervous System
Background:
- Chronic intractable ventricular tachycardia leads to significant morbidity and mortality.
- Intracardiac ablation may fail to provide relief for refractory arrhythmias.
- Sympathetic nerve interruption via thoracoscopic sympathectomy is an alternative treatment option.
Purpose of the Study:
- To present a series of thoracoscopic sympathectomy procedures for chronic, recurrent, and intractable ventricular tachycardia.
- To evaluate the safety and efficacy of sympathectomy in patients with refractory cardiac arrhythmias.
Main Methods:
- Retrospective review of sympathectomy records from January 2018 to February 2024 at a large academic medical center.
- Collected data included patient procedures, cardiovascular history, hospital course, postoperative outcomes, and mortality.
- Analysis of 20 patients who underwent sympathectomy for refractory cardiac arrhythmias.
Main Results:
- Twenty patients underwent thoracoscopic sympathectomy for refractory cardiac arrhythmias.
- Postoperative outcomes varied, with some patients experiencing symptom reduction or remission, while others required further treatment or transplantation.
- The procedure was generally well-tolerated, with a low rate of surgery-related mortality.
Conclusions:
- Thoracoscopic sympathectomy is a well-tolerated procedure in critically ill patients with refractory cardiac arrhythmias.
- A significant proportion of patients experienced symptom reduction or complete remission, suggesting its consideration in select cases.
- Sympathectomy should be considered as a therapeutic option for patients with refractory arrhythmias unresponsive to other treatments.
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