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Coronary Artery Bypass Grafting to Acute Marginal Branch: Forgotten Coronary Artery
Samuel Ricci1, Hiromu Kehara1, Sean M Baskin2
1Division of Cardiovascular Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Insights
Coronary artery bypass grafting to the acute marginal branch (AMB) improved right ventricular function. This surgical intervention may benefit patients with pulmonary hypertension and right ventricular dysfunction.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pulmonary Hypertension
Background:
- Current coronary artery bypass grafting (CABG) prioritizes left ventricular function.
- Right ventricular dysfunction is linked to increased mortality and morbidity.
- The impact of acute marginal branch (AMB) bypass on right ventricular function requires evaluation.
Purpose of the Study:
- To assess the effect of AMB bypass on right ventricular function.
- To identify predictors of improved right ventricular function after AMB bypass.
Main Methods:
- Retrospective review of 134 patients undergoing AMB bypass.
- Comparison of pre- and postoperative right heart catheterization data.
- Surgical indication: significant stenosis in the right coronary artery across AMB or AMB lumen size >1.5 mm.
Main Results:
- Median age 63 years, 97% male; 22% had preoperative right ventricular dysfunction.
- Significant reduction in right atrial pressure and pulmonary artery pressures.
- Increased pulmonary artery pulsatility index and cardiac index observed.
- Preoperative pulmonary artery pressures and pulsatility index predicted improved postoperative outcomes.
Conclusions:
- CABG to AMB enhances right ventricular function.
- AMB bypass is potentially beneficial for patients with pulmonary hypertension and right ventricular dysfunction.
- Further research is needed to confirm the impact on long-term survival.
Background:
Current practice for coronary artery bypass grafting focuses on left ventricular function, whereas there is increasing recognition right ventricular dysfunction is associated with a higher risk of mortality and morbidity. We evaluated the impact of acute marginal branch (AMB) bypass on right ventricular function.
Methods:
We reviewed 134 patients who underwent AMB bypass, comparing pre- and postoperative right heart catheter data. The surgical indication for AMB revascularization was multiple significant stenosis in right coronary artery across AMB or significant stenosis in AMB with lumen size of >1.5 mm.
Results:
The median age was 63 years, and 97 were male. The median preoperative left ventricular ejection fraction was 55%, and 22% of patients had right ventricular dysfunction by echocardiography. One hundred twenty-one (90%) cases were done by off-pump. The median number of anastomoses was 5. Saphenous vein graft was used in most cases (96%) and mainly done in sequential fashion (84%). There was a significant reduction in right atrial pressure, and diastolic and mean pulmonary artery pressure. Conversely, there was a notable increase in pulmonary artery pulsatility index and cardiac index. Preoperative mean pulmonary artery pressure and preoperative pulmonary artery pulsatility index were identified as significant independent predictors of improved post-operative pulmonary artery pulsatility index.
Conclusions:
Our initial investigation indicated coronary artery bypass grafting to AMB enhanced right ventricular function. This approach appeared to be advantageous for patients with preoperative pulmonary hypertension and right ventricular dysfunction. Additional research comparing coronary artery bypass grafting with and without AMB bypass is necessary to elucidate the true impact of this surgical intervention on right ventricular function and long-term survival.
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