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Related Experiment Video

Updated: Jun 11, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

Transcatheter Aortic Valve Explant Experience From a High-Volume Structural Heart Center.

Allen A Razavi1, Derrick Y Tam1,2, Aasha Krishnan1

  • 1Department of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.

Annals of Thoracic Surgery Short Reports
|June 10, 2026
PubMed
Summary

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Transcatheter aortic valve replacement (TAVR) explantation is a viable strategy when repeat TAVR is not possible. A high-volume center study found low morbidity and mortality for TAVR explantation, suggesting centralized care may improve outcomes.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Medical Device Technology

Background:

  • Transcatheter aortic valve replacement (TAVR) explantation is considered when TAVR fails and reintervention is not feasible.
  • Multicenter studies report high morbidity and mortality associated with TAVR explantation.
  • This study evaluates early and late outcomes of TAVR explantation at a high-volume structural heart center.

Purpose of the Study:

  • To assess the early and late outcomes of TAVR explantation procedures.
  • To compare outcomes between isolated surgical aortic valve replacement (SAVR) and SAVR with concomitant procedures following TAVR explantation.
  • To evaluate the safety and efficacy of TAVR explantation in a high-volume setting.

Main Methods:

  • A retrospective analysis of patients who underwent SAVR with a history of TAVR between 2011 and 2024 at a single high-volume center.

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Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

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Last Updated: Jun 11, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

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  • Comparison of outcomes at 30 days and 5 years between patients undergoing isolated SAVR versus SAVR with concomitant procedures after TAVR explantation.
  • Data extracted from the institutional The Society of Thoracic Surgeons registry.

    • Main Results:

    • TAVR implantations and explantations increased significantly over time.
    • Overall 30-day mortality was 7.4% and 30-day morbidity and mortality was 25.9%, considered relatively low.
    • No significant differences in 30-day mortality or 5-year survival were observed between isolated SAVR and concomitant procedures groups.

    Conclusions:

    • TAVR explantation at a high-volume center demonstrated relatively low rates of morbidity and mortality.
    • The findings suggest that centralization of care for complex TAVR explantation procedures may be beneficial.
    • Surgical aortic valve replacement following TAVR explantation is a safe and effective strategy, regardless of concomitant procedures.