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Updated: Jun 11, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
07:46

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia

Published on: May 9, 2013

Concomitant Carotid-Cerebral Artery Disease and Early Neurologic Complications After Coronary Artery Bypass Grafting

Yi Liu1,2, Wei Jin3,4, Zhijia Jin5

  • 1Department of Cardiovascular Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Annals of Thoracic Surgery Short Reports
|June 10, 2026
PubMed

Insights

Patients with carotid-cerebral artery disease face a higher risk of major neurologic complications, including stroke, delayed awakening, and severe delirium, following coronary artery bypass grafting (CABG). This finding highlights the importance of assessing cerebrovascular health before CABG surgery.

Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Vascular Disease

Background:

  • Neurologic complications, such as stroke, are significant risks associated with coronary artery bypass grafting (CABG).
  • Assessing the impact of concomitant carotid-cerebral artery disease on these complications is crucial for patient safety.

Purpose of the Study:

  • To investigate the association between coexisting carotid-cerebral artery disease and major neurologic complications after CABG.
  • To quantify the risk of stroke, delayed awakening, and severe delirium in patients with and without carotid-cerebral artery disease undergoing CABG.

Main Methods:

  • A cohort study included 1002 patients undergoing CABG between March 2020 and November 2022.
  • Preoperative computed tomography angiography identified carotid-cerebral artery disease (stenosis ≥50%).
  • Major neurologic complications within 7 days post-CABG were recorded as the primary outcome.

Main Results:

  • 10.4% of patients experienced early major neurologic complications.
  • Patients with carotid-cerebral artery disease showed a significantly higher risk of these complications (adjusted RR, 1.66; P = .015).
  • Increased stenosis severity correlated with a stepwise rise in neurologic complication incidence.

Conclusions:

  • Concomitant carotid-cerebral artery disease is linked to an increased risk of early major neurologic complications post-CABG.
  • These complications include stroke, delayed awakening, and severe delirium.
  • Preoperative evaluation of cerebrovascular status may aid in risk stratification for CABG patients.
Abstract

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