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Updated: Jun 11, 2026

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Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
Optical design concepts using wavelength-selective diffractive optics to enable miniaturized multimodal endoscopic
Summary
We developed a compact endoscopic imaging system using diffractive optical elements (DOEs) for multimodal imaging. This system enables simultaneous imaging across UV and infrared wavelengths, improving diagnostic capabilities.
Area of Science:
- Optical Engineering
- Biomedical Imaging
- Nanophotonics
Background:
- Multimodal imaging systems are crucial for advanced diagnostics.
- Miniaturization of endoscopic tools presents significant optical design challenges.
- Integrating multiple spectral bands into a single compact system requires innovative solutions.
Purpose of the Study:
- To present optical design concepts for a miniaturized multimodal endoscopic imaging system.
- To enable simultaneous imaging at the same sample plane across widely separated wavelength ranges (UV/short visible and 1300-1700 nm).
- To leverage diffractive optical elements (DOEs) for spectral band separation and optical design decoupling.
Main Methods:
- Utilized a scanning-fiber approach for beam delivery.
- Exploited wavelength-selective imaging properties of DOEs, using different diffraction orders for distinct spectral bands.
- Designed for high first-order diffraction efficiency in the UV/short visible region and zeroth-order operation in the 1300-1700 nm range.
- Analyzed three- and two-element optical designs featuring aspheric surfaces.
- Compensated for angular emission variations of the scanning fiber.
Main Results:
- Achieved simultaneous imaging in UV/short visible and 1300-1700 nm spectral bands using a single system.
- Demonstrated efficient collection of backward light propagation via fiber cladding, with potential enhancement using ring-shaped lenses and reflective surfaces.
- Validated compact system layouts with low-loss beam delivery.
Conclusions:
- The proposed optical design concepts enable miniaturized multimodal endoscopic imaging.
- The use of DOEs offers a versatile approach for spectral decoupling in compact systems.
- Further optimization of light collection could enhance system performance for endoscopic applications.

