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Updated: Jun 11, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[Sleep architecture changes and their impact on short-term ischemic stroke functional outcome]
L S Korostovtseva1, M V Bochkarev1, M A Bykova1
1Almazov National Medical Research Center, St. Petersburgh, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 10, 2026
Summary
Sleep disturbances after ischemic stroke impact functional recovery. Reduced total sleep time and NREM stage 2 sleep are linked to worse short-term outcomes, highlighting the need for sleep management in stroke rehabilitation.
Area of Science:
- Neurology
- Sleep Medicine
- Rehabilitation Medicine
Background:
- Stroke significantly impacts patient recovery and quality of life.
- Sleep disturbances are common post-stroke but their impact on functional outcome is not fully understood.
Purpose of the Study:
- To investigate the association between sleep macrostructure parameters and short-term functional outcomes after ischemic stroke.
Main Methods:
- An observational cohort study included 78 acute ischemic stroke patients.
- Full polysomnography was performed within 14 days of hospital admission.
- Linear regression analyses identified predictors of modified Rankin Scale (mRS) at discharge.
Main Results:
- Total sleep time and the proportion of NREM stage 2 sleep (NREM N2%) were independent predictors of mRS at discharge.
- Each additional hour of sleep correlated with a 0.15-point decrease in mRS.
- Increased NREM N2% was associated with a 0.032-point decrease in mRS.
Conclusions:
- Alterations in sleep macrostructure, including reduced total sleep time and NREM N2%, are associated with poorer short-term functional outcomes post-ischemic stroke.
- Integrating sleep disorder assessment and management into stroke rehabilitation strategies is recommended.
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