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Patch test sensitization and permanent tattoos: epidemiological data from two referral centers.

A Chiei Gallo1, F Barei2, C P Ratti1

  • 1Allergy and Clinical Immunology Unit, Sacco Hospital, Milan, Italy.

European Annals of Allergy and Clinical Immunology
|June 10, 2026
PubMed
Summary
This summary is machine-generated.

Eosinophilia in intensive care units (ICUs) affects 19% of patients, correlating with longer hospital stays and increased need for mechanical ventilation. This condition may serve as a marker for disease severity in critically ill patients.

Keywords:
Eosinophiliacritically illhypereosinophiliaintensive care unitorgan damage

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Area of Science:

  • Critical Care Medicine
  • Hematology

Background:

  • Eosinophilia is linked to mortality in hospitalized patients but remains understudied in intensive care units (ICUs).
  • Understanding eosinophilia's prevalence and impact in critically ill patients is crucial for improving outcomes.

Purpose of the Study:

  • To determine the prevalence of eosinophilia in intensive care unit (ICU) patients.
  • To investigate the association between eosinophilia and clinical outcomes, including mortality, mechanical ventilation, and vasoactive drug use.

Main Methods:

  • Retrospective cohort study using the Russian Intensive Care Dataset.
  • Defined eosinophilia as >0.5 x 10^9/L, with subgroup analysis for mild eosinophilia (0.5-1.5 x 10^9/L) and hypereosinophilia (>1.5 x 10^9/L).
  • Analyzed data from 2,082 ICU patients, focusing on primary endpoint of eosinophilia prevalence and secondary endpoints of mortality, mechanical ventilation, and vasoactive drug use.

Main Results:

  • Eosinophilia was observed in 19% (406/2,082) of ICU patients, including 2% with hypereosinophilia.
  • Patients with eosinophilia experienced longer hospital stays (41 vs. 32 days) and higher rates of mechanical ventilation (58.1% vs. 43.1%) and vasoactive drug use (24.6% vs. 17.0%).
  • Mortality was significantly higher in the hypereosinophilia group (29.5%) compared to those without eosinophilia (12%).

Conclusions:

  • Eosinophilia in ICU patients is associated with increased disease severity, indicated by longer hospital stays and greater need for critical care interventions.
  • The findings suggest that eosinophilia can serve as a valuable marker for disease severity in critically ill patients.
  • Further research into the mechanisms and management of eosinophilia in the ICU setting is warranted.