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Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
08:05

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

Published on: November 21, 2025

Peripheral nerve sensory fibers are recruited with less current and greater selectivity by conventional waveforms

Janie Provencher1,2, Harrison T Finn1,3, Janet L Taylor1,3,4,5

  • 1Spinal Cord Injury Research Centre, Neuroscience Research Australia, Randwick, New South Wales, Australia.

Journal of Applied Physiology (Bethesda, Md. : 1985)
|June 10, 2026
PubMed
Summary

High-frequency burst-modulated waveforms are less effective for recruiting sensory fibres during transcutaneous spinal stimulation compared to conventional waveforms. Conventional waveforms achieve sensory recruitment at lower intensities, making them more suitable for therapeutic applications.

Keywords:
H-reflexbiphasic/monophasic pulsehigh-frequency kilohertz waveformsneurostimulationperipheral nerve stimulation

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