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Endoscopic Procedures III: Video Capsule Endoscopy

Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...
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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Related Experiment Video

Updated: Jun 12, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

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Published on: July 7, 2023

Disposable Endoscope Cap Maintaining Clear Surgical Visualization under Fogging and Fouling.

Kayoung Son1, Yeontaek Lee1,2, Kyungwon Lee1,3

  • 1School of Electrical and Electronic Engineering, Yonsei University, Seoul 03722, Republic of Korea.

ACS Applied Materials & Interfaces
|June 10, 2026
PubMed
Summary
This summary is machine-generated.

A new endoscopic lens cap, SHIELD-C, uses a liquid interface to prevent fogging and contamination. This innovation maintains clear surgical visualization, improving patient safety and procedural flow.

Keywords:
anti-fogging surfaceendoscope accessoriesendoscopic surgerylens foulingvisualization stability

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Surgical Technology

Background:

  • Lens fogging and biological contamination are critical issues in endoscopic surgery, impairing visualization and patient safety.
  • Existing solutions often fail to provide sustained clarity or disrupt surgical workflow.

Purpose of the Study:

  • To develop and validate a novel endoscopic lens cap, SHIELD-C, designed to maintain stable visualization.
  • To address the unmet needs of lens fogging and biological fouling during endoscopic procedures.

Main Methods:

  • Development of SHIELD-C, a single-use cap with a dual-layer architecture: a polydimethylsiloxane (PDMS) brush base and an infused silicone oil top layer.
  • Formation of a stable liquid-liquid interface for optical clarity and antifouling properties.
  • Validation through in vitro tests under challenging conditions and ex vivo surgical models.

Main Results:

  • SHIELD-C demonstrated high optical clarity (>90% transmittance) and effective antifouling properties (sliding angle <10°).
  • The liquid interface allowed for rapid intraoperative restoration of clarity via lubricant replenishment.
  • Validated durability and optical stability in chemically and mechanically demanding tests and ex vivo models.

Conclusions:

  • SHIELD-C effectively maintains endoscopic visualization by creating a durable, superlubricious liquid-liquid interface.
  • This technology enhances the reliability and continuity of endoscopic procedures by mitigating lens fouling.
  • SHIELD-C represents a significant advancement in endoscopic surgical tools, improving safety and workflow.