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Related Concept Videos

Spectrophotometry: Introduction01:16

Spectrophotometry: Introduction

Spectrophotometry is the quantitative measurement of the absorption, reflection, diffraction, or transmission of electromagnetic radiation through a material as a function of the intensity and wavelength of the radiation. A spectrophotometer is a device used to measure the change in the radiation intensity caused by its interaction with the material.
The essential components of a spectrophotometer include a source of electromagnetic radiation, a slot for placing a material to be analyzed, and a...
Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations01:15

Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations

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Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
Instrument Calibration01:12

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Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
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Precipitation Titration: Endpoint Detection Methods01:19

Precipitation Titration: Endpoint Detection Methods

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Related Experiment Video

Updated: Jun 12, 2026

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
06:08

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

Published on: March 11, 2017

Detecting Secondary Medication Infusion Errors via Spectrophotometry.

Jeannine W C Blake, Aniruthan Saravanan, YeEun Lee

    Biomedical Instrumentation & Technology
    |June 10, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Intravenous smart pumps require specific hanger use for accurate secondary medication delivery. Incorrect setup, especially zero hanger height, leads to significant underdelivery and medication dilution, risking patient safety.

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    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

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    Last Updated: Jun 12, 2026

    Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
    06:08

    Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

    Published on: March 11, 2017

    Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
    11:17

    Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

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    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
    10:17

    High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

    Published on: April 23, 2019

    Area of Science:

    • Medical Devices
    • Clinical Engineering
    • Pharmacology

    Background:

    • Intravenous smart pumps (IVSPs) aim to minimize medication errors.
    • Many IVSPs rely on hydrostatic head height differential (HHD) for secondary medication delivery.
    • Poor clinical adherence to HHD requirements risks medication dilution and subtherapeutic dosing.

    Purpose of the Study:

    • To develop and validate a laboratory protocol for measuring delivered secondary medication concentration.
    • To quantify the risk of medication dilution and underdelivery associated with different IVSP hanger configurations and flow rates.

    Main Methods:

    • A laboratory protocol was developed to measure delivered secondary medication concentration.
    • Three hanger configurations (full, half, zero) were tested across various flow rates.
    • Delivered concentrations were analyzed for accuracy and deviation from intended values.

    Main Results:

    • Both hanger configuration and programmed flow rate significantly impacted delivered concentration (P < 0.0001).
    • Zero hanger configuration (zero HHD) resulted in severe underdelivery, often less than 50% of the intended concentration.
    • Full and half hanger configurations maintained accuracy up to 250 mL/h, with decreased accuracy at 400 mL/h for the half hanger.

    Conclusions:

    • The study validated a method for direct measurement of secondary medication delivery accuracy.
    • Clinical practice requires adherence to specific hanger configurations to ensure accurate medication delivery.
    • Findings can inform safer clinical practices and future IVSP device development.