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Prurigo nodularis en plaque resolved after a loading dose of nemolizumab
Seo Won Cho1, Helen Chen2, Aaron Chen1
1Department of Health Science Center, Texas A&M University Naresh K. Vashisht College of Medicine, Dallas, Texas, USA.
Proceedings (Baylor University. Medical Center)
|June 10, 2026
Abstract:
Prurigo nodularis is a chronic pruritic dermatosis often resistant to standard therapies. We report a patient with prurigo nodularis complicated by meralgia paresthetica who achieved complete and durable resolution of pruritus after a single loading dose of nemolizumab, an interleukin-31 receptor A (IL-31RA) antagonist. This case underscores the rapid efficacy of IL-31 blockade and highlights potential neuroimmune interplay in chronic itch disorders.
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