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Published on: December 5, 2019
Cross-Talk Between a Nematode Effector-Targeted Metabolic Enzyme and a Lectin Receptor Kinase Regulates Wheat
Fayu Li1, Wei Zhao1, Manyu Chen1
1Guangxi Key Laboratory of Agro-Environment and Agric-Products Safety, College of Agriculture, Guangxi University, Nanning 530004, China.
Journal of Agricultural and Food Chemistry
|June 10, 2026
Summary
Wheat resistance to cereal cyst nematodes involves a novel interaction between TaLecRK-S.4 and TaEMB3003. This interaction is modulated by nematode effectors, impacting plant immunity and susceptibility.
Area of Science:
- Plant pathology
- Molecular plant-microbe interactions
- Wheat genetics
Background:
- Cereal cyst nematode (Heterodera avenae) significantly impacts wheat production.
- Nematode effector HaGLAND5 suppresses host immunity by acetylating TaEMB3003, a key enzyme subunit.
Purpose of the Study:
- To elucidate the molecular mechanisms underlying nematode effector-triggered immune suppression in wheat.
- To identify novel host factors involved in wheat-nematode interactions.
Main Methods:
- Identification and characterization of wheat L-type lectin receptor kinase, TaLecRK-S.4.
- Demonstration of TaLecRK-S.4 interaction with TaEMB3003.
- Genetic analysis (overexpression and knockdown) of TaLecRK-S.4 in wheat.
Main Results:
- TaLecRK-S.4 interacts with TaEMB3003.
- Overexpression of TaLecRK-S.4 enhances wheat resistance to H. avenae.
- HaGLAND5-induced TaEMB3003 acetylation reduces TaEMB3003 and TaLecRK-S.4 protein levels.
Conclusions:
- A reciprocal regulatory model involving TaEMB3003 and TaLecRK-S.4 is proposed.
- Nematode effectors reprogram host signaling, linking metabolic changes to immune suppression.
- Findings offer new insights into plant-parasitic nematode interactions and wheat immunity.
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