Related Experiment Video

Updated: Jun 12, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

An extracellular allosteric gate modulates the ligand efficacy of GPR119

Yi Zhang1, Jiening Wang2, Zhen Han1

  • 1State Key Laboratory of Synthetic Biology, Haihe Laboratory of Sustainable Chemical Transformations, Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, Faculty of Medicine, School of Life Sciences, Tianjin University, Tianjin 300072, China.

Structure (London, England : 1993)
|June 10, 2026
PubMed

Keywords:
GPCRGPR119Partial Agonism

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