Neuroendocrine tumor of the gallbladder: An unusual location

Neuroendocrine tumors of the gallbladder are included among neuroendocrine tumors of uncommon location. Because they are non-functioning tumors, they usually do not produce symptoms and are often discovered at advanced stages. Their main differential diagnosis, due to gallbladder wall thickening, is acute cholecystitis. If imaging findings do not improve despite appropriate treatment, this entity should be considered in the differential diagnosis to achieve early treatment. Histopathological examination is the key to diagnosis. Small-cell neuroendocrine tumors with a high Ki-67 index have a poor prognosis and high short-term morbidity and mortality.