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Updated: Jun 12, 2026
06:39
Culture of myeloid dendritic cells from bone marrow precursors
Published on: July 25, 2008
Crystalline inclusions in myeloid precursors
1Unidade Local de Saúde de Santa Maria, Av. Prof. Egas Moniz, 1649-028, Lisbon, Portugal. marco.pinto@ulssm.min-saude.pt.
Journal of Hematopathology
|June 10, 2026
Summary
Crystalline inclusions are found in various blood cells, including those in aggressive myeloid neoplasms. Their presence in myeloid cells may indicate a more severe form of the disease.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Crystalline inclusions are observed in various immune and neoplastic cells.
- Their significance in myeloid malignancies is not fully understood.
Purpose of the Study:
- To investigate the association between crystalline inclusions and myeloid neoplasms.
- To determine if these inclusions are indicative of aggressive disease.
Main Methods:
- Literature review of cases with crystalline inclusions.
- Analysis of myeloid cell morphology in diagnosed cases.
Main Results:
- Crystalline inclusions documented in macrophages, plasma cells, chronic lymphocytic leukemia, and B-cell acute lymphoblastic leukemia.
- Rare occurrences noted in myeloid precursors.
Conclusions:
- Crystalline inclusions in myeloid cells may signify aggressive myeloid neoplasms.
- Further research is warranted to confirm this association.
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