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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

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Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography-Computed Tomography Scanner
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Evaluating multi-slice ptychography tomography for X-ray imaging.

Amey Luktuke, Yi Jiang, Junjing Deng

    Optics Express
    |June 11, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Multi-slice ptychographic tomography (MSPT) improves X-ray imaging of thick samples by modeling beam propagation. Informed initialization enhances depth resolution and reduces data needs for accurate nanoscale imaging.

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    Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography
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    Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

    Published on: May 27, 2008

    Area of Science:

    • X-ray imaging
    • Diffractive imaging techniques
    • Materials characterization

    Background:

    • X-ray ptychography commonly uses single-slice reconstruction, which is inaccurate for thick samples or high numerical aperture optics due to multiple scattering artifacts.
    • Multi-slice ptychographic tomography (MSPT) models beam propagation through specimens, reducing angular sampling needs for tomography.

    Purpose of the Study:

    • To systematically evaluate the performance of MSPT.
    • To understand how object thickness, optical parameters, and initialization strategies impact reconstruction accuracy.
    • To demonstrate the benefits of MSPT for nanoscale imaging.

    Main Methods:

    • Numerical simulations of X-ray propagation through specimens.
    • Analysis of experimental X-ray datasets using MSPT.
    • Systematic variation of object thickness, optical parameters, and initialization strategies.
    • Evaluation of reconstruction accuracy and artifact reduction.

    Main Results:

    • Informed object initialization significantly improves depth resolution in MSPT reconstructions.
    • Accurate projection extension using MSPT reduces angular sampling requirements for tomographic reconstruction.
    • MSPT demonstrates reduced artifacts compared to traditional methods in experimental data.

    Conclusions:

    • MSPT is a robust approach for nanoscale imaging at synchrotron facilities.
    • Optimized initialization strategies are crucial for maximizing MSPT performance.
    • MSPT overcomes limitations of single-slice methods for imaging complex or thick samples.