Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Understanding the ocular accumulation of mefuparib and its N-dealkylation metabolite: Pharmacokinetics, melanin affinity, and cellular disposition.

Experimental eye research·2026

Same author

Identification of Chemokine-Related Genes Derived From T and NK Cells in the Tumour Microenvironment of Ovarian Cancer Based on scRNA-Seq.

IET systems biology·2026

Same author

Application of a novel LC-MS-based proteomic workflow for host cell protein monitoring and risk control in biotherapeutics.

Antibody therapeutics·2026

Same author

Inhibition of aerobic glycolysis suppresses ferroptosis via activation of the AMPK-FoxO3a pathway in epileptic rats.

Molecular biology reports·2026

Same author

Harnessing Interpenetration for High Proton Conductivity in Zirconium Metal-Organic Frameworks.

Inorganic chemistry·2026

Same author

Fluorinative Rearrangement of Vinyl Diazo Compounds Enabled by a New Reactivity Mode of Cyclopropanediazonium Ions.

Angewandte Chemie (International ed. in English)·2026

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Case Report: dynamic monocyte reprogramming during ALSS therapy in type B HBV-ACLF revealed by single-cell

Jiale Xie¹, Jiahua Liu¹, Feiyu Wang²

¹Department of Gastroenterology, The Second Hospital of Hebei Medical University, Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology, Hebei Clinical Research Center for Digestive Diseases, Shijiazhuang, Hebei, China.

Frontiers in Immunology

|June 11, 2026

Summary

This summary is machine-generated.

Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) treatment with artificial liver support systems (ALSS) reprogrammed monocytes. A pro-inflammatory monocyte subpopulation (Mono4) decreased, suggesting ALSS impacts systemic inflammation in HBV-ACLF patients.

Area of Science:

Immunology
Hepatology
Genomics

Background:

Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) involves intense inflammation and immune dysregulation.

Keywords:

HBV-related acute-on-chronic liver failure artificial liver support system case report monocyte single-cell RNA sequencing

More Related Videos

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Published on: March 14, 2011

Related Experiment Videos

Last Updated: Jun 12, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

Published on: March 14, 2011

Monocytes are key players in HBV-ACLF progression.

Artificial liver support system (ALSS) is a common treatment for HBV-ACLF.