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Updated: Jun 12, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

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Published on: April 26, 2024

Is Night Shift Work Associated With Depression and Suicidal Ideation? A 17-Year Follow-Up Study.

María Romero-Parra¹, Antonio García-Hermoso², Rodrigo Yáñez-Sepúlveda³

¹Department of Nursing, Universitat de València.

Workplace Health & Safety

|June 11, 2026

Summary

Long-term night shift work increases mental health risks, particularly suicidal ideation and depression in women. Men experienced different depressive symptoms. Sex-specific interventions are needed.

Keywords:

depression shift work suicidal ideation workforce

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Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments

Published on: August 8, 2019

Area of Science:

Occupational Health
Mental Health Research
Sociology

Background:

Night shift work is linked to mental health issues, but long-term effects and sex differences are not well understood.
Previous research has not fully explored the specific impacts of sustained night shift schedules on psychological well-being.
Understanding these disparities is crucial for targeted health interventions.

Purpose of the Study:

To investigate the association between long-term night shift work and mental health outcomes.
To assess potential sex differences in the relationship between night shift work and mental health.
To utilize multivariable regression models for robust analysis.

Main Methods:

Analysis of data from 9,057 participants in the National Longitudinal Study of Adolescent Health (Add Health).
Utilized binomial generalized linear models to estimate relative risks (RR) and 95% confidence intervals (CIs).
Conducted interaction tests for night shift and sex, followed by sex-stratified analyses.

Main Results:

Long-term night shift work (17 years) was associated with increased suicidal ideation (RR=2.30) and depression (RR=1.46) in women.
Men showed associations between night shift work and specific depressive symptoms like feeling unhappy (RR=1.69) and feeling blue (RR=2.04).
Women also reported increased risks for feeling sad (RR=1.79) and feeling blue (RR=1.87) with night shift work.

Conclusions:

Long-term night shift work poses significant mental health risks, including suicidal ideation and depression, predominantly in women.
Findings highlight sex-specific susceptibility to adverse mental health outcomes related to night shift work.
Emphasizes the necessity for tailored, sex-specific interventions to mitigate these risks, especially for female night shift workers.