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Related Experiment Video

Updated: Jun 13, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

State-of-the-Art Imaging and Localization Assessment in Post-Operative Deep Brain Stimulation for Parkinson's

Kezia Tanesha Susanto, Brian Premchand, Kai Rui Wan

    Stereotactic and Functional Neurosurgery
    |June 11, 2026
    PubMed
    Summary

    Accurate electrode placement is crucial for deep brain stimulation (DBS) in Parkinson's disease (PD). Post-operative imaging, using MRI and CT scans, verifies lead position and guides programming for improved treatment outcomes.

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    Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

    Published on: August 12, 2018

    Area of Science:

    • Neurosurgery
    • Medical Imaging
    • Neurology

    Background:

    • Deep brain stimulation (DBS) is a key therapy for Parkinson's disease (PD), requiring precise electrode placement.
    • Post-operative imaging is vital for confirming lead accuracy and managing complications.

    Purpose of the Study:

    • To review current post-operative imaging techniques for DBS in PD.
    • To evaluate quantitative localization methods and their precision.
    • To discuss future directions for enhanced DBS assessment.

    Main Methods:

    • Review of current literature on post-operative imaging (CT, MRI) and localization techniques in DBS for PD.
    • Analysis of imaging resolution, anatomical contrast, and artifact characterization.
    • Discussion of automated software pipelines (e.g., Lead-DBS) for precise localization.

    Main Results:

    • CT provides high resolution for electrode visualization, while MRI offers superior anatomical detail.
    • Image registration techniques are standard, with automated pipelines achieving precision within ±0.5-1.5 mm.
    • Both modalities have distinct advantages and limitations for DBS assessment.

    Conclusions:

    • Accurate post-operative imaging is essential for effective DBS in Parkinson's disease.
    • Advancements in automated and multimodal imaging pipelines promise improved accuracy and clinical utility.
    • Personalized imaging strategies are key for optimizing DBS therapy.