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Related Experiment Video

Updated: Jun 13, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

Exploring the Patient Pathway to Focused Ultrasound Ablation for Essential Tremor: A Mixed-Method Approach.

Nicole A Silva, Ariana Hernandez, Alok K Dwivedi

    Stereotactic and Functional Neurosurgery
    |June 11, 2026
    PubMed
    Summary

    Focused ultrasound ablation (FUSA) for Essential Tremor (ET) shows significant delays and barriers. Women and lower socioeconomic status patients face longer waits and worse quality of life, with women less likely to undergo FUSA.

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    Area of Science:

    • Neurology
    • Neurosurgery
    • Medical Economics

    Background:

    • Essential Tremor (ET) is a common neurological disorder.
    • Focused Ultrasound Ablation (FUSA) is an emerging treatment for medication-refractory ET.
    • Disparities in access to ET treatments are known, but barriers to FUSA are understudied.

    Purpose of the Study:

    • To investigate socioeconomic and gender-based barriers to Focused Ultrasound Ablation (FUSA) for Essential Tremor (ET).
    • To analyze delays in diagnosis and treatment, quality of life (QOL), and factors influencing FUSA uptake.

    Main Methods:

    • A mixed-methods study at a single tertiary-care center.
    • Inclusion of medication-refractory ET patients seeking FUSA consultation.
    • Quantitative analysis (regression, Fisher's exact test) and qualitative analysis (questionnaires, focus groups).

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    Last Updated: Jun 13, 2026

    MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
    05:54

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    Published on: December 13, 2017

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    Main Results:

    • Patients experienced long delays: ~10 years for diagnosis/treatment and 4 years for FUSA consultation.
    • Women had more provider contacts pre-diagnosis (7.5 vs. 0.9) and worse QOL.
    • Lower socioeconomic status patients faced longer diagnostic (15 vs. 3.3 yrs) and FUSA consultation delays (35 vs. 10.2 yrs).
    • Despite worse QOL, women were less likely to undergo FUSA (4 vs. 10 men).

    Conclusions:

    • Significant socioeconomic and gender disparities exist in the patient pathway to FUSA for ET.
    • Women experience worse QOL due to tremor but are less likely to receive FUSA.
    • Patient-centered interventions are crucial to ensure equitable access to FUSA for ET patients.