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Published on: October 1, 2007
Geometric Control of Pressure-Driven Infiltration in Microfluidic Channels
Aniruddha Saha1, Joshua Krsek1, Giancarlo D'Orazio1
1Department of Mechanical and Aerospace Engineering, Cornell University, Ithaca 14853-0001, New York, United States.
Langmuir : the ACS Journal of Surfaces and Colloids
|June 11, 2026
Summary
Channel geometry, not just surface chemistry, can control liquid flow in microchannels. Sinusoidal profiles create capillary barriers for stepped meniscus motion, offering a new geometric strategy for passive flow regulation.
Area of Science:
- Microfluidics
- Fluid Dynamics
- Materials Science
Background:
- Pressure-driven infiltration in microchannels is typically managed via surface chemistry.
- The influence of channel geometry on this process is less explored.
Purpose of the Study:
- To investigate the role of channel geometry in regulating pressure-driven infiltration.
- To demonstrate how sinusoidal channel profiles can control liquid advancement.
Main Methods:
- Development of an analytical force-balance model including pressure, capillary forces, and viscous dissipation.
- High-speed synchrotron X-ray radiography of 3D-printed microchannels.
- Application of a conformal iCVD fluoropolymer coating to modify wettability.
Main Results:
- Sinusoidal channel profiles create periodic capillary barriers, leading to stepped meniscus motion.
- Experimental results confirmed the model's predictions of interface arrest and release events.
- Geometric control of infiltration was achieved independently of surface chemistry.
Conclusions:
- Channel geometry offers a viable strategy for passive flow regulation in microfluidic systems.
- Sinusoidal profiles enable precise tuning of pressure-driven infiltration.
- This geometric approach complements surface chemistry methods for flow control.
