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Updated: Jun 13, 2026

Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
Published on: March 7, 2018
Connecting transcriptional control to RNA velocity and cell fate
1IDG/McGovern Institute for Brain Research, State Key Laboratory of Molecular Oncology, MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Pharmaceutical Sciences, Tsinghua Medicine, Tsinghua University, Beijing, China.
Abstract:
RNA velocity can predict the direction of cell-state change, but the regulatory programs shaping these changes remain difficult to identify. In this issue of Cell, Wang et al. introduce RegVelo, a framework that integrates gene regulatory networks into RNA velocity analysis to nominate candidate regulators that may bias cell fate.
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