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Updated: Jun 13, 2026

Visualizing the DNA Damage Response in Purkinje Cells Using Cerebellar Organotypic Cultures
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Suppression of ATM kinase signaling accelerates cellular senescence

Kei-Ichi Ishikawa1, Takahiro Shiga2, Takumi Hirose2

  • 1Center for Genomic and Regenerative Medicine, Juntendo University School of Medicine, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.

Stem Cell Reports
|June 11, 2026
PubMed

Keywords:
ATM kinaseAlzheimer’s diseaseKU60019Parkinson’s diseasecellular senescencehuman induced pluripotent stem cellsneurodegenerative disease modelingneuronal maturation

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