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Risk factors associated with early complications in pediatric patients diagnosed with acute pancreatitis
C A González-Heredia1, A Y Martínez-Vázquez2, F E Hernández-Lara-González3
1Departamento de Pediatría, Hospital para el Niño Poblano, Puebla, Mexico.
Insights
This study identified significant risk factors for early complications in pediatric acute pancreatitis. Early assessment of disease severity and timely interventions are crucial for managing this condition in children.
Area of Science:
- Pediatric Gastroenterology
- Clinical Research
- Epidemiology
Background:
- Acute pancreatitis is increasingly recognized in children, with complication rates up to 30%.
- Understanding risk factors is vital for improving outcomes in pediatric acute pancreatitis.
Purpose of the Study:
- To identify variables associated with early complications in pediatric acute pancreatitis.
- To determine risk factors for disease progression in children.
Main Methods:
- Retrospective analysis of 143 pediatric patients diagnosed with acute pancreatitis.
- Statistical analysis using odds ratio (OR) to identify risk factors.
- Data collected from July 2014 to July 2024 at Hospital para el Niño Poblano.
Main Results:
- The most frequent complications included cardiac (51.75%), renal (31.47%), pulmonary (18.18%), and metabolic (16.08%).
- Local complications observed were pancreatic necrosis (16%) and peripancreatic fluid collection (12.6%).
- A slight female predominance was noted (51%).
Conclusions:
- Significant risk factors for early complications in pediatric acute pancreatitis were identified.
- Findings support early disease severity assessment.
- Timely interventions can be guided by identified risk factors.
Introduction And Aim:
Acute pancreatitis is a rare condition in pediatric patients, but there has been a considerable increase in cases and complications in recent years that, according to the literature, may reach up to 30% of cases. The present study aimed to determine whether the variables of sex, age group, etiology, nutritional status, lipase level, albumin level, and leukocyte count were associated with the development of early complications in pediatric patients diagnosed with acute pancreatitis.
Materials And Methods:
A retrospective study was carried out at the Hospital para el Niño Poblano, within the time frame of July 2014 and July 2024. The medical records of patients from 0 to 17 years 11 months of age, who met the diagnostic criteria for acute pancreatitis, were analyzed. JASP software was utilized for the statistical analysis, applying odds ratio (OR) to identify possible risk factors.
Results:
A total of 143 patients were included, with a slight predominance of females (51%, n = 73). Of the local complications, pancreatic necrosis was documented in 16% (n = 23) and acute peripancreatic fluid collection in 12.6% (n = 18). The most frequent complications were cardiac (51.75%), renal (31.47%), pulmonary (18.18%), and metabolic (16.08%).
Conclusion:
Significant risk factors for the development of early complications in pediatric patients with acute pancreatitis were identified. These findings may support early assessment of disease severity and guide timely interventions.
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Pathophysiology
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

