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Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

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Related Experiment Video

Updated: Jun 13, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
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Diffusion Tensor Imaging Correlates of Financial Capacity Instrument-Short Form Completion Time in Mild Cognitive

Daniel A Stevens1,2, Kylie Alm3, Arnold Bakker3,4

  • 1Mental Health Care Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston.

The Journal of Neuropsychiatry and Clinical Neurosciences
|June 12, 2026
PubMed
Summary
This summary is machine-generated.

Financial task completion time may indicate early Alzheimer's disease changes. Slower performance in individuals with mild cognitive impairment (MCI) correlated with white matter changes, suggesting potential for early detection.

Keywords:
Alzheimer’s DiseaseCognitive DisordersFinancial CapacityMild Cognitive Impairment

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Published on: October 13, 2016

Area of Science:

  • Neuroscience
  • Gerontology
  • Radiology

Background:

  • Financial independence relies on accurate task completion.
  • Early Alzheimer's disease (AD) can impair financial capacity, leading to loss and caregiver burden.
  • Slower financial task performance may signal early cognitive decline.

Purpose of the Study:

  • To investigate the link between financial task completion time and white matter diffusion characteristics in older adults with and without mild cognitive impairment (MCI).

Main Methods:

  • Diffusion MRI scans and neuropsychological assessments were performed on 15 MCI patients and 15 healthy controls.
  • Diffusion tensor imaging analyzed white matter tracts.
  • Correlations were examined between Financial Capacity Instrument-Short Form (FCI-SF) completion times and diffusion metrics.

Main Results:

  • Participants with MCI showed significantly longer FCI-SF completion times than controls.
  • No significant differences in diffusion metrics were found across selected white matter tracts between groups.
  • FCI-SF completion time correlated with diffusion metrics in specific white matter tracts (arcuate, vertical occipital, inferior longitudinal fasciculi) in MCI individuals.

Conclusions:

  • Financial Capacity Instrument-Short Form (FCI-SF) completion times may reflect early, subtle white matter changes.
  • These changes are in tracts associated with reading and arithmetic, potentially indicating early AD-related cognitive alterations.