The Role of Natural Anthelmintics in Small Ruminant Health: A Global Narrative Review
Tiziana Maria Mahayri1, Alessia Serra1, Filomena Dessì1
1Department of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Animals : an Open Access Journal From MDPI
|June 12, 2026
Summary
Sustainable alternatives like natural anthelmintics are crucial for controlling gastrointestinal nematodes in small ruminants due to rising drug resistance. Research should focus on real-world validation and cost-benefit analyses for effective integration.
Area of Science:
- Veterinary Parasitology
- Sustainable Agriculture
- Natural Product Chemistry
Background:
- Gastrointestinal nematodes (GINs) significantly impact small ruminant health and productivity.
- Anthelmintic resistance necessitates exploring sustainable parasite control strategies.
- Natural anthelmintics offer promising alternatives to conventional drugs.
Purpose of the Study:
- To review the host-parasite dynamics in small ruminants concerning GINs.
- To evaluate the efficacy, mechanisms, and safety of natural anthelmintics.
- To discuss the integration of natural agents into parasite management programs.
Main Methods:
- Literature review of host-parasite interactions and GINs.
- Analysis of natural anthelmintic compounds (tannins, saponins, essential oils, etc.).
- Assessment of GIN impact on animal productivity and resistance.
Main Results:
- Natural anthelmintics show potential for controlling GINs and improving productivity.
- Various natural agents possess distinct mechanisms against nematodes.
- Host resistance, tolerance, and resilience are key factors in GIN management.
Conclusions:
- Natural anthelmintics are vital for integrated parasite control in small ruminants.
- Further research is needed for real-world validation, safety, and cost-effectiveness.
- Successful integration requires robust scientific evidence and practical application strategies.
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