Related Experiment Videos
Impact of Passive Smoking on Vital Signs, Motor Activity, and Agitation in Children Undergoing Dental Extractions
Elif Buse Kaplan1, Aysun Avşar1
1Department of Pediatric Dentistry, Faculty of Dentistry, Ondokuz Mayıs University, 55280 Samsun, Türkiye.
Insights
Passive smoking exposure in children undergoing dental sedation negatively impacts oxygen saturation, prolongs recovery, and increases agitation and delirium. Preoperative assessment should include environmental tobacco smoke exposure. Keywords: passive smoking, dental sedation, pediatric recovery, emergence delirium.
Area of Science:
- Pediatric Anesthesiology
- Environmental Health
- Dental Public Health
Background:
- Passive smoking (PS) is linked to systemic and oral health issues in children.
- Its impact on perioperative stability during pediatric dental sedation is not well understood.
Purpose of the Study:
- To investigate the association between passive smoking exposure and perioperative physiological stability, recovery, and emergence behavior in children undergoing dental sedation.
Main Methods:
- Prospective cohort study of 100 children (4-6 years) undergoing dental extraction under sedation.
- Stratified groups based on passive smoking exposure levels.
- Monitored vital signs (HR, BP, SpO2) and assessed recovery using MASS, RASS, and PAED scales.
Main Results:
- Passive smoking exposure correlated with significantly lower SpO2 levels (p < 0.001).
- Prolonged recovery time (p = 0.002) and increased agitation/emergence delirium (higher RASS and PAED scores, p < 0.001) were observed in exposed children.
- No significant differences in cardiovascular parameters were noted.
Conclusions:
- Passive smoking adversely affects perioperative oxygenation and recovery in children undergoing dental sedation.
- It exacerbates emergence neurobehavioral disturbances, including agitation and delirium.
- Environmental tobacco exposure should be part of preoperative risk assessments.
Background And Aim:
Passive smoking (PS) is a well-established risk factor associated with systemic and oral health impairments in children. However, its influence on perioperative physiological stability and recovery profiles during pediatric dental sedation remains insufficiently elucidated. This study investigated the association between PS exposure and perioperative vital parameters, recovery characteristics, and emergence behavioral outcomes in children undergoing dental extractions under sedation.
Methods:
This prospective cohort study (ClinicalTrials.gov: NCT06780189) included 100 ASA I children aged 4-6 years scheduled for primary molar extraction under midazolam-remifentanil-propofol sedation. Participants were stratified into three groups: no exposure, caregiver and household exposure, and household exposure only. An exposure-related relationship was evaluated based on daily household cigarette consumption. Perioperative vital signs (HR, blood pressure, and SpO2) were continuously monitored. Postoperative recovery and emergence profiles were assessed using the Modified Aldrete Recovery Score (MASS), Richmond Agitation-Sedation Scale (RASS), and Pediatric Anesthesia Emergence Delirium (PAED) scale.
Results:
Children exposed to PS demonstrated significantly lower SpO2 levels across all perioperative phases compared with non-exposed counterparts (p < 0.001), reflecting an exposure-related effect. In contrast, no statistically significant differences were observed in cardiovascular parameters (p > 0.05). Recovery time was significantly prolonged in PS-exposed children (p = 0.002). Furthermore, PS exposure was associated with significantly higher RASS and PAED scores, indicating increased agitation and emergence delirium (p < 0.001).
Conclusions:
Passive smoking adversely affects perioperative oxygenation, delays recovery, and exacerbates emergence neurobehavioral disturbances in children undergoing dental sedation. Environmental tobacco exposure must be integrated into preoperative risk assessments.
Related Concept Videos
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...