Racial and Ethnic Disparities in the Management and Outcomes of Acute Myocardial Infarction Complicated by
Maninder Randhawa1, Dylan Yu1, Anand Rai1
1Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI 49007, USA.
Insights
Racial and ethnic disparities impact acute myocardial infarction (AMI) outcomes with ventricular arrhythmias (VAs). Hispanic and other groups faced higher mortality, while Black, Hispanic, and other groups received less intervention for AMI with VAs.
Area of Science:
- Cardiology
- Health Disparities Research
- Inpatient Outcomes Analysis
Background:
- Ventricular arrhythmias (VAs) are a significant complication of acute myocardial infarction (AMI), leading to increased morbidity and mortality.
- Understanding racial and ethnic disparities in AMI management and outcomes is crucial but remains incomplete.
Purpose of the Study:
- To investigate racial and ethnic disparities in the management and in-hospital outcomes of patients with AMI complicated by VAs.
- To compare outcomes and procedural utilization across different racial and ethnic groups.
Main Methods:
- Retrospective analysis of 902,398 hospitalizations with AMI and VAs from 2002-2022 using the National Inpatient Sample.
- Stratification of hospitalizations by race/ethnicity (White, Black, Hispanic, Other).
- Comparison of baseline characteristics and in-hospital outcomes, including mortality and procedural interventions (PCI, CABG, ICD).
Main Results:
- Hispanic and other racial/ethnic groups had higher odds of in-hospital mortality compared to White patients.
- Black, Hispanic, and other racial/ethnic groups had lower odds of percutaneous coronary intervention (PCI) compared to White patients.
- Black patients had lower odds of coronary artery bypass grafting (CABG) and implantable cardioverter-defibrillator (ICD) insertion compared to White patients.
Conclusions:
- Significant racial and ethnic disparities exist in the prevalence, management, and in-hospital outcomes of AMI complicated by VAs.
- Differences in care were observed across racial and ethnic groups, particularly in procedural interventions.
- Further research and targeted interventions are necessary to address these disparities in high-risk patient populations.
Abstract:
Background: Ventricular arrhythmias (VAs) represent a high-risk complication of acute myocardial infarction (AMI) and are associated with high morbidity and mortality. Racial and ethnic disparities in the management and in-hospital outcomes of AMI with VAs remain incompletely understood. Methods: Using the National Inpatient Sample, we conducted a retrospective analysis of hospitalizations in which AMI was complicated by VAs from 2002 to 2022. Hospitalizations were stratified by race/ethnicity including White, Black, Hispanic, and other racial/ethnic groups. Baseline characteristics and in-hospital outcomes were compared across groups. Results: We identified 902,398 hospitalizations in which AMI was complicated by VAs, of which 78.2% occurred among White, 9.6% among Black, 6.3% among Hispanic, and 5.9% among patients of other racial/ethnic groups. Compared with White patients, Hispanic (aOR 1.21; CI 1.14-1.28) and patients in other racial/ethnic groups (aOR 1.31; CI 1.24-1.39) had higher odds of in-hospital mortality while Black patients had similar odds. In terms of procedural utilization, Black (aOR 0.65; CI 0.62-0.68), Hispanic (aOR 0.82; CI 0.77-0.86), and other racial/ethnic groups (aOR 0.89; CI 0.85-0.94) all had lower odds of percutaneous coronary intervention (PCI) relative to White patients. Black patients also had lower odds of coronary artery bypass grafting (CABG) (aOR 0.69; CI 0.64-0.74) and implantable cardioverter-defibrillator (ICD) insertion (aOR 0.84; CI 0.74-0.96) compared with White patients during admission. Conclusions: Racial and ethnic disparities exist in the prevalence, management, and in-hospital outcomes of AMI complicated by VAs. Further efforts are needed to address differences in care in this high-risk population.
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