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Related Experiment Video

Updated: Jun 13, 2026

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents
07:42

Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents

Published on: April 25, 2017

Male Urinary Incontinence Severity and Non-Adjustable Sling Outcomes: Protocol for a Multivariate Dose-Response

Emilio Sacco1, Francesco Pio Bizzarri1, Marco Campetella1

  • 1Department of Urology, Ospedale Isola Tiberina-Gemelli Isola, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Journal of Clinical Medicine
|June 12, 2026
PubMed
Summary

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This summary is machine-generated.

This systematic review will analyze how male stress urinary incontinence (UI) severity impacts non-adjustable sling treatment outcomes. Findings aim to improve patient selection and surgical decision-making for better UI management.

Area of Science:

  • Urology
  • Surgical Innovation
  • Evidence-Based Medicine

Background:

  • Male stress urinary incontinence (UI) significantly impacts quality of life, especially post-prostatectomy.
  • Non-adjustable male slings are a common treatment, but their efficacy relative to UI severity is unclear.
  • Objective metrics for UI severity are crucial for predicting treatment success.

Purpose of the Study:

  • To conduct a systematic review and dose-response meta-analysis.
  • To investigate the association between preoperative UI severity and outcomes of non-adjustable male slings.
  • To provide quantitative evidence for improved patient selection and counseling.

Main Methods:

  • Comprehensive literature search across major databases (PubMed, Web of Science, Scopus, Cochrane).
Keywords:
dose–responsemalemeta-analysisprostatectomyprotocolsplinessystematic reviewurethral slingurinary incontinence

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Last Updated: Jun 13, 2026

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  • Inclusion of RCTs and observational studies with objective UI severity metrics and ≥6 months follow-up.
  • Dose-response meta-analysis to assess linear/nonlinear associations, with subgroup/meta-regression analyses for heterogeneity.

    • Main Results:

    • Primary outcomes: failure to achieve cure or overall success (cure/meaningful improvement).
    • Study quality assessed using QUIPS tool.
    • Certainty of evidence graded using GRADE framework, adhering to PRISMA guidelines.

    Conclusions:

    • This analysis will offer quantitative insights into UI severity and male sling efficacy.
    • Findings will support evidence-based decision-making in surgical management of male stress UI.
    • Improved patient selection and counseling are anticipated outcomes.