Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel Biomarker for Antimitochondrial Antibodies in Systemic Sclerosis Patients.

Journal of immunology research·2026
Same author

Mapping emotional function in fibromyalgia: integrating alexithymia, pain catastrophizing, and self-compassion.

Therapeutic advances in musculoskeletal disease·2026
Same author

Fear-avoidance beliefs toward physical activity in axial spondyloarthritis and psoriatic arthritis: insights from a cross-sectional study.

Clinical and experimental rheumatology·2026
Same author

Metabolomic profile differs between LADA and type 1 diabetes identifying tryptophan metabolism as a pathway involved in the heterogeneity of autoimmune diabetes.

Diabetologia·2026
Same author

Clinical associations and related factors of metabolic syndrome in systemic sclerosis: results from an observational multicenter study of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale).

Rheumatology international·2026
Same author

Real-world damage accrual in Sjögren's disease: a 5-year multicentre GIRRCS cohort analysis.

RMD open·2026

Related Experiment Video

Updated: Jun 13, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Disease Activity-Related Sleep Dysfunction in Psoriasis: Insights from a Cross-Sectional Study.

Damiano Currado1,2, Claudio Conforti3, Francesca Trunfio1

  • 1Rheumatology and Clinical Immunology, Department of Medicine, University of Rome Campus Biomedico, School of Medicine, 00128 Rome, Italy.

Journal of Clinical Medicine
|June 12, 2026
PubMed
Summary

Psoriasis (PsO) disease severity is linked to specific sleep problems like longer sleep latency and daytime dysfunction, not overall sleep quality. Addressing these sleep issues is key for comprehensive PsO patient care.

Keywords:
PASIpsoriasissleep quality

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Related Experiment Videos

Last Updated: Jun 13, 2026

Measuring Psoriasis Severity at Home
02:28

Measuring Psoriasis Severity at Home

Published on: March 1, 2024

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Area of Science:

  • Dermatology
  • Sleep Medicine
  • Psychosomatic Medicine

Background:

  • Psoriasis (PsO) is a chronic immune-mediated disease with a significant burden beyond skin symptoms.
  • Sleep disturbances are an under-recognized aspect of patient-reported outcomes in PsO.
  • Understanding the link between PsO activity and sleep is crucial for holistic patient management.

Purpose of the Study:

  • To investigate the relationship between PsO disease activity and specific sleep domains.
  • To determine if PsO severity independently predicts sleep latency and daytime dysfunction.

Main Methods:

  • Cross-sectional study of 136 PsO patients from two Italian centers.
  • Disease severity assessed by Psoriasis Area and Severity Index (PASI).
  • Sleep quality evaluated using Pittsburgh Sleep Quality Index (PSQI); quality of life by SF-36.
  • Statistical analysis included univariable and multivariable ordinal regression models.

Main Results:

  • Patients with higher PsO disease activity (PASI ≥ 10) reported significantly worse sleep latency and greater daytime dysfunction.
  • No significant differences in global PSQI scores were observed between disease severity groups.
  • Multivariable analysis confirmed PASI ≥ 10 as an independent predictor of increased sleep latency and daytime dysfunction.

Conclusions:

  • Increased PsO disease activity is independently associated with impaired sleep latency and daytime dysfunction.
  • The impact of PsO on sleep is domain-specific, affecting specific aspects rather than overall sleep quality.
  • Integrating domain-specific sleep assessments into PsO management is essential for patient-centered care.