Related Experiment Video
Updated: Jun 13, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Transphyseal Proximal Humeral Aneurysmal Bone Cyst with Pathologic Fracture in a Child: A Case Report
Taichun Li1, Jingmiao Wang1, Qin Zhang2
1Department of Pediatric Orthopedics, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200062, China.
Aneurysmal bone cyst (ABC) is a rare pediatric bone lesion. This case highlights the diagnostic challenges of transphyseal extension in the proximal humerus, emphasizing multimodality assessment for accurate diagnosis.
Area of Science:
- Orthopedic Surgery
- Pediatric Radiology
- Skeletal Pathology
Background:
- Aneurysmal bone cyst (ABC) is a benign, locally aggressive osteolytic lesion common in pediatric long bones.
- Transphyseal extension of ABC into the epiphysis, especially in the proximal humerus, is rare and poses diagnostic challenges due to overlapping imaging features with other conditions.
- Differential diagnoses include unicameral bone cyst and telangiectatic osteosarcoma.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Formation by Endochondral Ossification
