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Diffuse Large B-Cell Lymphoma Causing Melena, Gastric Ulcer, Liver Mass, and Hypercalcemia
Jose J Sanchez1, Deanne Kashiwagi1
1Hospital Medicine, Mayo Clinic, Rochester, USA.
Cureus
|June 12, 2026
Summary
This case report details an elderly woman with diffuse large B-cell lymphoma (DLBCL), presenting with anemia and hypercalcemia. The diagnosis was confirmed via biopsies of gastric and hepatic lesions.
Area of Science:
- Oncology
- Hematology
- Internal Medicine
Background:
- Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
- Uncommon presentations of DLBCL can delay diagnosis and treatment.
- Hypercalcemia is a potential paraneoplastic manifestation of lymphoma.
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