Related Experiment Video
Updated: Jun 13, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Systematic gastric surveillance in patients with familial adenomatous polyposis
Hicham Bouchiba1,2,3, Dewkoemar Ramsoekh1,2,3, Arthur S Aelvoet1,2,3
1Department of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, The Netherlands.
Background And Aims:
Familial adenomatous polyposis (FAP) has shown a rising incidence of gastric cancer, particularly in the proximal stomach. We aimed to demonstrate a systematic protocol to improve gastric surveillance in FAP.
Methods:
The protocol consists of systematic gastric examination using white-light endoscopy and narrow-band imaging combined with patient repositioning from the left lateral to supine position in cases with carpeting fundic gland polyposis.
Results:
Three FAP cases illustrate the diagnostic value of this approach. In 2 cases, supine repositioning improved visualization of mucosa obscured by carpeting fundic gland polyps. In the third case, an ulcerated adenocarcinoma hidden among polyps with the patient in the left lateral position became visible only after repositioning.
Conclusions:
Systematic gastric surveillance with advanced imaging and patient repositioning can reveal lesions not visible on standard inspection. This approach may enhance early detection of premalignant and malignant gastric lesions in FAP.
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