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Related Experiment Video

Updated: Jun 13, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
04:00

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Axial length-based reference values for corneal sensitivity in a pediatric population.

Irem Onal1,2, Begum Aydin3, Yusuf Berk Akbas3

  • 1Department of Ophthalmology, University of Health Sciences, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey. iiremonal@gmail.com.

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|June 12, 2026
PubMed
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This summary is machine-generated.

Children with longer axial lengths (AL) have reduced corneal sensitivity (CS). Specifically, eyes with AL ≥ 26 mm showed significantly lower CS across all quadrants compared to shorter AL eyes.

Area of Science:

  • Ophthalmology
  • Corneal Physiology
  • Pediatric Eye Care

Background:

  • Axial length (AL) is a key determinant of ocular growth and refractive error.
  • Corneal sensitivity (CS) plays a crucial role in maintaining ocular surface health and integrity.
  • Understanding the relationship between AL and CS in pediatric populations is essential for early detection of potential visual impairments.

Purpose of the Study:

  • To investigate the relationship between axial length (AL) and corneal sensitivity (CS) in healthy pediatric eyes.
  • To establish preliminary reference values for corneal sensitivity across different AL categories in children.
  • To determine if axial elongation is associated with altered corneal sensory function in pediatric populations.

Main Methods:

  • A prospective, cross-sectional study involving 353 children aged 5-18 years.
Keywords:
Axial myopiaCochet–Bonnet esthesiometerCorneal sensitivityHigh myopia

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  • Axial length (AL) was categorized into four groups (≤22 mm, 22.01-23.99 mm, 24.0-25.99 mm, ≥26 mm).
  • Corneal sensitivity (CS) was measured in five quadrants using a Cochet-Bonnet esthesiometer, with statistical analyses performed across AL and age groups.

    • Main Results:

    • Corneal sensitivity (CS) significantly differed across axial length (AL) groups in all measured corneal quadrants (p < 0.001 to 0.009).
    • Eyes with AL ≥ 26 mm exhibited significantly reduced CS in all quadrants compared to eyes with AL ≤ 22 mm (p ≤ 0.002).
    • A weak negative correlation between AL and CS was observed (r = -0.125 to -0.212), with AL independently associated with lower CS after adjusting for age, sex, and central corneal thickness (CCT).

    Conclusions:

    • Corneal sensitivity (CS) varies across different axial length (AL) groups in pediatric eyes, being notably lower in eyes with AL ≥ 26 mm.
    • The association between longer axial length and reduced corneal sensitivity persists even after adjusting for key demographic and ocular parameters.
    • These findings provide preliminary reference data for pediatric CS and suggest that axial elongation may impact corneal sensory function, warranting further investigation.