Regional data, global lessons: what the Asia-Pacific osteoporosis audit teaches the world
Manju Chandran1,2, Paul Mitchell3,4, Peter R Ebeling5,6
1Department of Endocrinology, Osteoporosis and Bone Metabolism Unit, Singapore General Hospital, Academia, 20 College Road, Singapore, 169856, Singapore. Manju.chandran@singhealth.com.sg.
Abstract:
The APCO-IOF Asia Pacific Regional Audit on the epidemiology, costs and burden of osteoporosis 2025 is not just a regional report; it is a systems stress test for global osteoporosis preparedness and ageing. Across 22 countries, structural gaps recur: incomplete fracture surveillance, uneven diagnostic access, misaligned reimbursement, and limited secondary fracture prevention. These are not failures of knowledge but of system design. The lessons are universal: count fractures, define quality, fund post-fracture pathways, develop coherent guidelines, align financing with risk, and track outcomes. Osteoporosis is not a niche specialty concern but a defining test of how health systems respond to demographic ageing.
Related Concept Videos
Osteoclasts in Bone Remodeling
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Remodeling
Peripheral Artery Disease III: Interprofessional Care
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
