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Updated: Jun 14, 2026

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
07:47

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Published on: September 26, 2020

BioPrinted Hearts.

Janet Rae-Dupree

    IEEE Pulse
    |June 12, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Stanford researchers are developing bioprinting technology to create new hearts from patient cells. This "moonshot" project aims for pig heart transplants by 2028, overcoming significant bioengineering challenges.

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    Area of Science:

    • Regenerative Medicine
    • Biotechnology
    • Bioengineering

    Background:

    • Significant advancements in regenerative medicine are crucial for addressing organ shortages.
    • Bioprinting offers a promising avenue for creating functional organs.
    • Developing patient-specific organs can mitigate immune rejection post-transplant.

    Purpose of the Study:

    • To develop foundational technologies for bioprinting functional human hearts.
    • To overcome key hurdles in creating living cardiac tissue and vascular structures.
    • To advance the goal of transplanting a bioprinted heart into a pig by 2028.

    Main Methods:

    • Utilizing a multi-disciplinary approach with experts in bioengineering, stem cell biology, and computational science.
    • Scaling up stem cell production to organ-level quantities.

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    Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
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    Related Experiment Videos

    Last Updated: Jun 14, 2026

    Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
    07:47

    Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

    Published on: September 26, 2020

    Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting
    04:40

    Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting

    Published on: July 2, 2017

    Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
    08:22

    Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

    Published on: August 11, 2017

  • Developing novel 3-D printing technology capable of printing complex tissues and vascular networks rapidly.
  • Main Results:

    • Achieved organ-scale stem cell production.
    • Developed a new technology for printing tissues and vascular structures within a semi-solid gel.
    • Created a novel 3-D printer that prints complex tissues quickly enough for cell survival.

    Conclusions:

    • Progress has been made in stem cell production and tissue printing for cardiac bioprinting.
    • Challenges remain in supporting bioprinted tissue via synthesized vascular trees.
    • The project is on track to potentially achieve pig heart transplantation by 2028.